Really not sure how this is going to turn out considering it's going to be multi platform (360, PC and PS3) meaning the dreaded 'Loading' from DX2: IW might be evident to cater for the consoles lack of RAM between rooms.
What I loved about the first one (Island of Liberty) was that it was FPS but you could interact with almost every object in the world, not to mention the story was excellent. What I hate about the current wave of FPS' is that there's hardly any plot and you just shoot for the fun of it.
Really looking forward to this, I even bout IoL for PC (GOTY Edt.) back in the day :).
http://en.wikipedia.org/wiki/Deus_Ex_3
http://games.on.net/app/3225/Deus_Ex_Human_Evolution